|
|
S-adenosyl-L-methionine + L-Dopa <=> methyl_3-hydroxy-L-tyrosinate + S-adenosyl-L-homocysteine + H+
|
2.1.1.6
catechol O-methyltransferase
|
–
|
|
BRENDA:
BS409647
MetaCyc:
RXN-10870
|
|
|
|
methyl_3-hydroxy-L-tyrosinate + 2-oxoglutarate <=> 3-methoxy-4-hydroxyphenylpyruvate + L-glutamate
|
2.6.1.5
tyrosine transaminase
|
–
|
|
BRENDA:
BS356677
MetaCyc:
RXN-10871
|
|
|
|
3-methoxy-4-hydroxyphenylpyruvate + NADH + H+ <=> 3-(3-methoxy-4-hydroxyphenyl)lactate + NAD+
|
1.1.1.237
hydroxyphenylpyruvate reductase
|
–
|
|
BRENDA:
BS187867
MetaCyc:
RXN-10872
|
|
|
|
3-methoxy-4-hydroxyphenylpyruvate <=> homovanillic_acid
|
not assigned
|
–
|
|
MetaCyc:
RXN-10877
|
|